The methodology for asymmetric conjugate addition reactions has been explored for organocopper reagents. These studies have proven to be very useful in efforts to establish 1,3-syn and 1,3-anti stereochemistry in acyclic systems.
Primary references: Tet. Lett. 2002, 43, 3723-3727; Chem. Commun. 2003, 2220-2221.
Synthesis applications in capensifuranone: J. Org. Chem. 2004, 19, 5374-5382.
Efforts toward kendomycin: Org. Lett. 2005, 7, 4161-4164.
Examples in the synthesis of (+)-sambutoxin: Org. Lett. 2000, 2, 3217-3220.